What is garcinia extract

Several studies have investigated the effect of garcinia cambogia on weight loss in people. Less research has been done on other uses of garcinia cambogia. Several dozen cases of liver toxicity have been reported in people who were taking products labeled as containing garcinia cambogia. What Have We Learned? A review of 11 short-term studies in people did not find significant effects of garcinia cambogia products on weight loss. Cases of liver damage associated with the use of garcinia cambogia products have been reported.

This problem appears to be uncommon, but some cases were severe. Most of the reported cases involved products labeled as containing a combination of ingredients, but some involved products labeled as containing only garcinia cambogia. Other side effects associated with garcinia cambogia include headache and nausea, diarrhea, and other gastrointestinal symptoms.

Keep in Mind. Take charge of your health—talk with your health care providers about any complementary health approaches you use. Therefore, it may be a good idea to take a few weeks off every three months or so. Follow the dosage instructions on the label. Garcinia cambogia is a fruit-derived supplement taken to boost weight loss, though studies disagree on its effectiveness. Some research shows that it may cause slightly more weight loss than not taking any supplement.

This effect is unconfirmed but promising. That said, if you really want to lose weight, you might have better luck by changing your diet and lifestyle. A supplement produced from an exotic fruit, garcinia cambogia, is the latest weight-loss craze. But the Internet and television are filled with…. Both garcinia cambogia and apple cider vinegar are claimed to promote weight loss.

This article reviews the evidence behind combining garcinia…. Plexus Slim is a powdered weight loss supplement that you mix with water and drink. It contains 4 active ingredients claimed to help you lose weight. Countless supplements on the market claim to offer a quick way to drop excess weight by suppressing your appetite. This is a detailed review of forskolin, a popular weight loss supplement that has been shown to be effective in some human studies.

This is a science-based review of Hydroxycut, one of the world's most popular weight loss supplements. It contains caffeine and several herbal…. Here is a detailed look at 10 evidence-based natural appetite suppressants that can help you lose weight. Chromium picolinate is a supplemental form of chromium said to improve nutrient metabolism and promote weight loss. This article examines the evidence…. Getting good quality sleep is an important part of weight loss.

Here are a few ways sleep can help you lose weight. Keywords: Dietary supplements, Fulminant hepatic failure, Drug-induced liver injury, Liver transplantation, Hyroxycitric acid, Weight-loss supplements. Table 1 Work-up for causes of acute liver failure in reported patient. Open in a separate window.

Figure 1. COMMENTS Case characteristics The patient initially presented with symptoms of nausea, vomiting, abdominal pain, and symptoms progressed to include confusion, coagulopathy, and jaundice. Clinical diagnosis Evaluation for viral, genetic, and antibody mediated causes of hepatitis were largely negative with histological evidence of near total hepatic necrosis on biopsy.

Differential diagnosis Alternative autoimmune, viral, and genetic causes of acute liver failure must be excluded. Laboratory diagnosis Negative laboratory evaluation for autoimmune, viral, and genetic causes of acute liver failure in the presence of elevated liver function tests and coagulopathy should raise clinical suspicion for drug-induced liver injury. Imaging diagnosis Magnetic resonance imaging with Eovist contrast demonstrated interval development of heterogeneous, enhancing nodularity with portal venous washout, unlikely to be an infiltrative tumor process.

Pathological diagnosis Explant pathology demonstrated near total hepatic necrosis with massive hepatocellular dropout and mixed inflammatory cell infiltrates. Treatment Patient received liver transplantation with complete resolution of symptoms.

Related reports Acute liver failure and severe hepatotoxicity has been associated multiple dietary supplements utilized for weight loss. Term explanation Garcinia cambogia - tree grown in southwestern India. Experiences and lessons Careful questioning of any patient presenting with liver function abnormalities or acute liver failure should prompt questioning regarding dietary supplement and energy drink consumption.

Peer-review This article presents one of the first known cases of hepatotoxicity associated with intake of the dietary supplement Garcinia cambogia. References 1. Cohen PA. Hazards of hindsight--monitoring the safety of nutritional supplements. N Engl J Med. De Smet PA. Herbal remedies. Chitturi S, Farrell GC. Hepatotoxic slimming aids and other herbal hepatotoxins. J Gastroenterol Hepatol. Safety Reporting Portal: MarketData Enterprises I.

Tampa: FL; Successful weight loss among obese U. Am J Prev Med. Access date March 24, Garcinia cambogia hydroxycitric acid as a potential antiobesity agent: a randomized controlled trial. Hydroxycut-induced Liver Toxicity. Ann Med Health Sci Res. Hydroxycut hepatotoxicity: a case series and review of liver toxicity from herbal weight loss supplements.

Lobb A. Hepatoxicity associated with weight-loss supplements: a case for better post-marketing surveillance. Two patients with acute liver injury associated with use of the herbal weight-loss supplement hydroxycut.

Ann Intern Med. Shim M, Saab S. Severe hepatotoxicity due to Hydroxycut: a case report. Dig Dis Sci. Fatal liver failure following food supplements during chronic treatment with montelukast. Dig Liver Dis. Food and Drug Administration. Warning on Hydroxycut Products.

Garcinia cambogia can be found in Hydroxycut. The Food and Drug Administration FDA issued a consumer warning in cautioning consumers to immediately stop using Hydroxycut products after reports of jaundice and extreme liver damage in people who used Hydroxycut surfaced. Other health problems associated with Hydroxycut included seizures, cardiovascular disorders, and rhabdomyolysis.

A study from Japan found that rats fed high doses of garcinia cambogia lost significant fat. However, the high doses also caused testicular atrophy. In , pop television doctor Mehmet Oz announced to his audience that garcinia cambogia is a revolutionary fat buster. No Diet. No Effort.

In June , Dr. Oz was chided for making unwarranted claims about garcinia cambogia and other products in an appearance before the Senate Subcommittee on Consumer Protection, Product Safety, Insurance, and Data Security. Garcinia cambogia is available in capsules, tablets, powders, and liquids. Capsules should be taken on an empty stomach, 30 minutes to an hour before a meal. According to ConsumerLab. Instead, they found the doses were either too low or too high.

If you take the capsules, buy a reputable brand and make sure they contain at least 50 percent HCA.